SubtiBank SubtiBank
bsdC
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bsdC

phenolic acid decarboxylase
Locus
BSU_03640
Isoelectric point
5.12
Molecular weight
52.86 kDa
Protein length
473 aa Sequence Blast
Gene length
1422 bp Sequence Blast
Function
resistance to salicylic acid
Product
phenolic acid decarboxylase
Essential
no
Synonyms
yclC

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
413,157 → 414,578

The protein

Catalyzed reaction/ biological activity

  • conversion of vanillic acid to guaiacol PubMed
  • 4-hydroxybenzoate + H+ --> CO2 + phenol (according to UniProt)
  • 4-hydroxy-3-methoxybenzoate + H+ --> CO2 + guaiacol (according to UniProt)
  • Protein family

  • ubiD family (single memberm, according to UniProt)
  • Structure

  • 5M1B (from E. coli, 31% identity) PubMed
  • Expression and Regulation

    Operons

    Description

    Regulatory mechanism

  • BsdA: activation, PubMed, in BsdA regulon
  • Regulation

  • induced by salicylic acid (BsdA) PubMed
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    Biological materials

    Mutant

  • MGNA-C062 (yclC::erm), available at the NBRP B. subtilis, Japan
  • BKE03640 (ΔbsdC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TCTGAAATCTTGATAAGCCA, downstream forward: _UP4_AATAAATAAGGAAAGGATGT
  • BKK03640 (ΔbsdC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_TCTGAAATCTTGATAAGCCA, downstream forward: _UP4_AATAAATAAGGAAAGGATGT
  • References

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