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ypcP [2019-01-29 10:43:24]
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ypcP [2019-01-29 10:43:24]

5'->3' exonuclease
locus
BSU22010
pI
5.22
mw
32.79 kDa
protein length
296 aa Sequence Blast
gene length
888 bp Sequence Blast
function
protection of developing and dormant spores against UV DNA damage
product
5'->3' exonuclease
essential
no
synonyms
exoA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]

    • Gene

    Coordinates
    2,310,995 → 2,311,885

    The protein

    Paralogous protein(s)

  • [protein|3D6DA8B52A4CB49361E67906140696FFA1EF6099|PolA]:

    • Structure

  • [PDB|1BGX] (Taq polymerase, 36% identity) [pubmed|9770525]

    • Expression and Regulation

    Operons

    genes
    [gene|FCDE5EA6E50A8C72A499E2F1FFB808DC86466A29|exoR]
    description
    [pubmed|22383849]
    view in new tab

    Biological materials

    Mutant

  • MGNA-B868 (exoA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1867 NBRP B. subtilis, Japan]
  • BKE22010 (Δ[gene|FCDE5EA6E50A8C72A499E2F1FFB808DC86466A29|exoR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE22010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAAATAACTCCCTTTTC, downstream forward: _UP4_GCTAGAGAGATCGTTTAGAT
  • BKK22010 (Δ[gene|FCDE5EA6E50A8C72A499E2F1FFB808DC86466A29|exoR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK22010 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAAATAACTCCCTTTTC, downstream forward: _UP4_GCTAGAGAGATCGTTTAGAT

    • References

  • 17114254,17905985,16045613,30096406,9770525