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sr1 [Fri Dec 09 2016 16:57:35 GMT+0100 (CET)]
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sr1 [Fri Dec 09 2016 16:57:35 GMT+0100 (CET)]

small regulatory RNA controlling AhrC expression, regulatory peptide
locus
BSU14629
pI
4.00
mw
4.00 kDa
function
control of arginine metabolism and glycolysis
product
small regulatory RNA, regulatory peptide
essential
no
synonyms
ykzW
Outlinks
KEGGBsubCycUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.4|Biosynthesis/ acquisition of arginine]
  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.4|Utilization of arginine/ ornithine]
  • [category|SW 6|Groups of genes] → [category|SW 6.9|NcRNA] → [category|SW 6.9.5|Regulatory RNAs]

    • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis/ acquisition of amino acids], [SW|utilization of amino acids], [SW|ncRNA]

    • This gene is a member of the following [SW|regulons]

  • [SW|CcpN regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,534,120 -> 1,534,239

    The protein

    Catalyzed reaction/ biological activity

  • hybridizes to ''[protein|search|ahrC]'' mRNA and inhibits [protein|search|AhrC] translation. [Pubmed|17020585]

    • = Extended information on the RNA=

    Protein family

  • the peptide is conserved in bacilli

    • [SW|Interactions]

  • [protein|search|GapA]-[protein|search|YkzW] [Pubmed|20444087]

    • Additional information

  • Information on the structure of the RNA can be found in [Pubmed|17020585]
  • =The peptide=

    • = Extended information on the protein =

    [SW|Interactions]:

  • [protein|search|GapA]-[protein|search|YkzW] [Pubmed|20444087]

    • Expression and Regulation

    Operon

  • sr1 [Pubmed|16164558]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|16164558]

    • Regulation

  • Repressed in the presence of glucose by [protein|search|CcpN] [Pubmed|16164558]

    • Regulatory mechanism

  • transcription repression [Pubmed|16164558]

    • Biological materials

    Mutant

  • 168 sr1::cat, available in [SW|Brantl] lab
  • GP2210 (''[protein|search|sr1]''::''cat''), available in [SW|Jörg Stülke]'s lab

    • Labs working on this gene/protein

  • [SW|Sabine Brantl], Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany [http://www.uni-jena.de/AG_Bakteriengenetik_(_Doz__Dr__Sabine_Brantl_).html homepage]

    • References

  • 16164558,17020585,17576690,20444087