sr1 [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

small regulatory RNA controlling AhrC expression, regulatory peptide

Locus: BSU14629

Isoelectric point: 4.00

Molecular weight: 4.00 kDa

Function: control of arginine metabolism and glycolysis

Product: small regulatory RNA, regulatory peptide

Essential: no

Synonyms: ykzW

Genomic Context

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Categories containing this gene/protein

• Metabolism → Amino acid/ nitrogen metabolism → Biosynthesis/ acquisition of amino acids → Biosynthesis/ acquisition of arginine
• Metabolism → Amino acid/ nitrogen metabolism → Utilization of amino acids → Utilization of arginine/ ornithine
• Groups of genes → NcRNA → Regulatory RNAs

Categories containing this gene/protein

• biosynthesis/ acquisition of amino acids, utilization of amino acids, ncRNA

This gene is a member of the following regulons

• CcpN regulon

Gene

Coordinates on the chromosome (coding sequence): 1,534,120 -> 1,534,239

The protein

Catalyzed reaction/ biological activity

• hybridizes to ahrC mRNA and inhibits AhrC translation. PubMed

= Extended information on the RNA=

Protein family

• the peptide is conserved in bacilli

Interactions

• GapA-YkzW PubMed

Additional information

• Information on the structure of the RNA can be found in PubMed
• =The peptide=

= Basic information/ Evolution =

• 'Catalyzed reaction/ biological activity:' the peptide controls the stability of the cggR-gapA mRNA PubMed
• 'Protein family:' the peptide is conserved in bacilli
• '''Paralogous protein(s):

= Extended information on the protein =

• '''Kinetic information:
• '''Domains:
• '''Modification:
• '''Cofactor(s):
• '''Effectors of protein activity:
• '''Interactions:
• GapA-YkzW PubMed
• '''Localization:

= Database entries =

• 'BsubCyc:' BSU14629
• '''Structure:
• 'UniProt:' C0H410
• '''KEGG entry:
• '''E.C. number:

Expression and Regulation

Operon

• sr1 PubMed

Sigma factor

• SigA PubMed

Regulation

• Repressed in the presence of glucose by CcpN PubMed

Regulatory mechanism

• transcription repression PubMed

Biological materials

Mutant

• 168 sr1::cat, available in Brantl lab

Labs working on this gene/protein

• Sabine Brantl, Bacterial Genetics, Friedrich-Schiller-University of Jena, Germany homepage

References

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