SubtiBank SubtiBank
hxlB
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hxlB

6-phospho-3-hexuloisomerase
Locus
BSU_03450
Isoelectric point
5.79
Molecular weight
19.82 kDa
Protein length
185 aa Sequence Blast
Gene length
558 bp Sequence Blast
Function
ribulose monophosphate pathway for formaldehyde fixation
Product
6-phospho-3-hexuloisomerase
Essential
no
E.C.
5.3.1.27
Synonyms
yckF

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
374,603 → 375,160

The protein

Catalyzed reaction/ biological activity

  • D-arabino-hex-3-ulose 6-phosphate --> β-D-fructose 6-phosphate (according to UniProt)
  • Protein family

  • SIS family (single member, according to UniProt)
  • Domains

  • SIS domain (aa 29-172) (according to UniProt)
  • Structure

    Expression and Regulation

    Operons

    Genes
    Description

    Regulatory mechanism

  • HxlR: activation, PubMed, in HxlR regulon
  • Regulation

  • induction by formaldehyde (HxlR) PubMed
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    Biological materials

    Mutant

  • MGNA-C056 (yckF::erm), available at the NBRP B. subtilis, Japan
  • BKE03450 (ΔhxlB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_GTATTCAGTCGTTTTCATCG, downstream forward: _UP4_TAGCATCACACAACCGGCCT
  • BKK03450 (ΔhxlB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_GTATTCAGTCGTTTTCATCG, downstream forward: _UP4_TAGCATCACACAACCGGCCT
  • References

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