cotD [Mon Aug 31 2015 13:55:13 GMT+0200 (CEST)]

spore coat protein (inner)

locus: BSU22200

pI: 7.37

mw: 8.00 kDa

function: resistance of the spore

product: spore coat protein (inner)

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.7|Class VI]

[SW|Categories] containing this gene/protein

• [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|GerE regulon], [SW|SigK regulon], [SW|SpoIIID regulon]

The protein

Protein family

• nhaC Na(+)/H(+) antiporter family (according to Swiss-Prot)

[SW|Localization]

• inner spore coat [Pubmed|19933362], localization depends on [protein|search|SafA] [Pubmed|22171814]

Expression and Regulation

Operon

• ''cotD'' [Pubmed|22383849]

[SW|Sigma factor]

• [protein|search|SigK] [Pubmed|15699190]

Regulation

• expressed late during sporulation in the mother cell ([protein|search|SigK], [SW|SpoIIID], [protein|search|GerE]) [Pubmed|15383836,15699190,7966271]

Regulatory mechanism

• [SW|SpoIIID]: transcription repression [Pubmed|7966271]
• [protein|search|GerE]: transcription activation [Pubmed|15383836]

Biological materials

Mutant

• 1S104 ( ''cotD''::''cat''), [Pubmed|2821284], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S104&Search=1S104 BGSC]

References

Reviews

• 23202530

Original publications

• 19933362,1518043,2821284,2492118,1691789,14651647,15699190,7966271,22171814,15383836