SubtiBank SubtiBank
cstA
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cstA

similar to pyruvate transporter, carbon starvation-induced protein
Locus
BSU_28710
Isoelectric point
8.66
Molecular weight
64.19 kDa
Protein length
598 aa Sequence Blast
Gene length
1797 bp Sequence Blast
Function
uptake of pyruvate
Product
putative pyruvate transporter, carbon starvation-induced protein
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Transporters → Transporters/ other → Other transporters
  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of organic acids
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    2,936,382 → 2,938,178

    The protein

    Catalyzed reaction/ biological activity

  • pyruvate:H+ symport PubMed

    • Protein family

  • peptide transporter carbon starvation (CstA) (TC 2.A.114) family (single member, according to UniProt)

    • Localization

  • membrane (according to UniProt)

    • Expression and Regulation

    Operons

    Genes
    cstA-ysfE
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

    • Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon

    • Regulation

  • repressed by glucose (3.4-fold) (CcpA) PubMed
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    Biological materials

    Mutant

  • MGNA-B012 (cstA::erm), available at the NBRP B. subtilis, Japan
  • BKE28710 (ΔcstA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTCTCCCATCCCCTTT, downstream forward: _UP4_TAGAAGGACTATTGAAAATG
  • BKK28710 (ΔcstA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTCTCCCATCCCCTTT, downstream forward: _UP4_TAGAAGGACTATTGAAAATG

    • References

    The E. coli homolog

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