csbA

general stress protein, required for protection against paraquat stress

locus: BSU_35180

pI: 9.30

mw: 8.33 kDa

protein length: 76 aa

gene length: 231 bp

function: protection against paraquat stress

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 3,615,116 → 3,615,346

The protein

[SW|Localization]

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• genes: [gene|F8FDCE60F815597F228D8D1E6E05149EDF69835D|csbA]
  description: [Pubmed|1744042]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|1744042], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|1744042,15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

  regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|1744042,15805528]

Biological materials

Mutant

• MGNA-A393 (csbA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/393 NBRP B. subtilis, Japan]
• BKE35180 (Δ[gene|F8FDCE60F815597F228D8D1E6E05149EDF69835D|csbA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE35180 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACAAAAACCCTCCTCAGG, downstream forward: _UP4_TAAATCGGACATAATGAATA
• BKK35180 (Δ[gene|F8FDCE60F815597F228D8D1E6E05149EDF69835D|csbA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK35180 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACAAAAACCCTCCTCAGG, downstream forward: _UP4_TAAATCGGACATAATGAATA

References

• 1744042,22582280,15805528