mutSB [2017-8-11 16:0:3]

probable DNA mismatch repair protein

locus: BSU28580

pI: 5.79

mw: 87.23 kDa

protein length: 785 aa

gene length: 2355 bp

function: DNA repair

product: probable DNA mismatch repair protein

essential: no

synonyms: yshD, mutS2

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]

Gene

Coordinates: 2,920,936 → 2,923,293

The protein

Protein family

• DNA mismatch repair mutS family (according to Swiss-Prot)

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|EAD44AA7D72510B70308FD0C9F159DBEDAEBBB74|zapA]-[gene|93726C423313C653C4F71CB107FA12F686959E41|yshB]-[gene|D3954F2BCF6CE66505E4F48FCB4A61EE8D24F6D3|polX]-[gene|F8E82D9AE514B31892FE4530532691274ADA682B|mutSB]-[gene|18CEF3F1EE2E95A009699DE370CBB44F025B7B40|yshE]
  description: [Pubmed|22383849]

  regulation

  • constitutively expressed [Pubmed|23701187]

Biological materials

Mutant

• MGNA-B007 (yshD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1006 NBRP B. subtilis, Japan]
• 1A845 ( ''mutSB''::''cat''), [Pubmed|11254128], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A845&Search=1A845 BGSC]
• 1A845 ( ''mutSB''::''cat''), [Pubmed|11254128], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A845&Search=1A845 BGSC]

Labs working on this gene/protein

• [SW|Alessandra Albertini], University of Pavia, Italy [http://www-1.unipv.it/genbiom/albertini.html homepage]

References

Reviews

• 22933559

Original publications

• 11254128,27799325