dTDP -4-dehydrorhamnose-3,5-epimerase, spore coat polysaccharide synthesis
function
rhamnose biosynthesis, spore coat polysaccharide synthesis
product
dTDP -4-dehydrorhamnose-3,5-epimerase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.7|Biosynthesis of rhamnose (for the exosporium)][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][SW|Categories] containing this gene/protein
[SW|miscellaneous metabolic pathways], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|GerE regulon], [SW|SigK regulon]Gene
Coordinates on the chromosome (coding sequence)
3,882,979 -> 3,883,434
The protein
Structure
[PDB|3RYK] (dTDP-4-dehydrorhamnose 3,5-epimerase (''rfbC'') from ''Bacillus anthracis'' str. Ames with TDP and PPi bound, 32% identity, 56% similarity)Expression and Regulation
Operon
''[protein|search|spsA]-[protein|search|spsB]-[protein|search|spsC]-[protein|search|spsD]-[protein|search|spsE]-[protein|search|spsF]-[protein|search|spsG]-[protein|search|spsI]-[protein|search|spsJ]-[protein|search|spsK]-[protein|search|spsL]'' [Pubmed|9353933][SW|Sigma factor]
[protein|search|SigK] [Pubmed|15383836]Regulation
expressed late during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|25239894,15383836]Regulatory mechanism
[protein|search|GerE]: transcription activation [Pubmed|25239894,15383836]References
9353933,15383836,22960854,25239894 
