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clpQ [Thu Jan 14 2016 18:06:56 GMT+0100 (CET)]
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clpQ [Thu Jan 14 2016 18:06:56 GMT+0100 (CET)]

two-component ATP-dependent protease
locus
BSU16150
pI
6.00
mw
19.00 kDa
function
protein degradation
product
two-component ATP-dependent protease
essential
no
synonyms
hslV, codW
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.4|Additional proteins involved in proteolysis]

    • [SW|Categories] containing this gene/protein

  • [SW|proteolysis], [SW|membrane proteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|CodY regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,688,114 -> 1,688,659

    The protein

    Protein family

  • HslV subfamily (according to Swiss-Prot)

    • Structure

  • [PDB|2Z3B]

    • [SW|Localization]

  • cytoplasm, forms small foci, usually positioned near the cell membrane, formation of foci depends on the presence of the cognate ATPase [protein|search|ClpY] [Pubmed|18689473]

    • [SW|Interactions]

  • [protein|search|ClpQ]-[protein|search|ClpY] [Pubmed|18689473]

    • Expression and Regulation

    Operon

  • ''[protein|search|codV]-[protein|search|clpQ]-[protein|search|clpY]-[protein|search|codY]'' [Pubmed|7783641]

    • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|7783641]

    • Regulation

  • repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|11331605]

    • Regulatory mechanism

  • [protein|search|CodY]: transcription repression [Pubmed|11331605]

    • References

    Reviews

  • 23479438,26639779

    • Original publications

  • 12805205,11179218,18689473,11331605,7783641