SubtiBank SubtiBank
queE [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]
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queE [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

7-carboxy-7-deazaguanine (CDG) synthase, required for the synthesis of the modified ribonucleotide queuosine
locus
BSU13740
pI
4.96
mw
26.00 kDa
function
tRNA modification
product
7-carboxy-7-deazaguanine (CDG) synthase
essential
no
synonyms
ykvL
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.8|tRNA modification and maturation]

    • [SW|Categories] containing this gene/protein

  • [SW|translation]

    • This gene is a member of the following [SW|regulons]

  • [SW|preQ1 riboswitch]

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,440,542 -> 1,441,273

    The protein

    Protein family

  • radical S-adenosyl-L-methionine (SAM) superfamily

    • [SW|Cofactors]

  • [4Fe-4S] cluster, S-adenosyl-L-methionine, Mg(2+) [Pubmed|23194065]

    • [SW|Interactions]

  • [protein|search|QueE]-[protein|search|YkuN] (electron transfer) [Pubmed|25933252]

    • Expression and Regulation

    Operon

  • ''[protein|search|queC]-[protein|search|queD]-[protein|search|queE]-[protein|search|queF]'' [Pubmed|14660578]

    • Regulation

  • repressed in the presence of queuosine ([SW|preQ1 riboswitch]) [Pubmed|19285444]

    • Regulatory mechanism

  • [SW|preQ1 riboswitch]: transcriptional antitermination in the absence of queuosine [Pubmed|19285444]

    • References

  • 14660578,19285444,19354300,17384645,24362703,23194065,25933252