SubtiBank SubtiBank
cwlP
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cwlP

cell wall hydrolase of the SP-beta prophage region,
Locus
BSU_21350
Isoelectric point
8.27
Molecular weight
252.01 kDa
Protein length
2285 aa Sequence Blast
Gene length
6858 bp Sequence Blast
Function
cell wall turnover
Product
cell wall hydrolase
Essential
no
Synonyms
yomI
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Cell envelope and cell division → Cell wall degradation/ turnover → Autolysis
  • Prophages and mobile genetic elements → Prophages → SP-beta prophage
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    2,249,154 → 2,256,011

    The protein

    Catalyzed reaction/ biological activity

  • hydrolyzes the peptidoglycan and cell wall of B. subtilis PubMed

    • Protein family

  • transglycosylase Slt family (together with CwlQ) (according to UniProt)

    • Domains

  • contains soluble lytic transglycosylase (SLT) and peptidase M23 domains PubMed
  • ten tetratrichopeptide repeats (according to UniProt)

    • Localization

  • cell membrane (according to Swiss-Prot)

    • Biological materials

    Mutant

  • BKE21350 (ΔcwlP::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAGTAAGAATCACTTCCTT, downstream forward: _UP4_TAAGAGTCTGCAAAAGCAGA
  • BKK21350 (ΔcwlP::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAGTAAGAATCACTTCCTT, downstream forward: _UP4_TAAGAGTCTGCAAAAGCAGA