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pksI [Tue Oct 25 2016 17:08:05 GMT+0200 (CEST)]
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pksI [Tue Oct 25 2016 17:08:05 GMT+0200 (CEST)]

involved in polyketide synthesis
Locus
BSU17170
Isoelectric point
5.00
Molecular weight
27.00 kDa
Function
polyketide synthesis
Product
unknown
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Miscellaneous metabolic pathways → Biosynthesis of antibacterial compounds
  • Lifestyles → Coping with stress → Biosynthesis of antibacterial compounds

    • Categories containing this gene/protein

  • miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

    • This gene is a member of the following regulons

  • AbrB regulon, CodY regulon

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,792,012 -> 1,792,761

    The protein

    Protein family

  • enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)

    • Structure

  • 4Q1G and 4Q1H (wildtype with different buffer components co-crystallized)
  • 4Q1I (A80K)
  • 4Q1J (A230H)
  • 4Q1K (A232K)

    • Expression and Regulation

    Operon

  • pksC-pksD-pksE-acpK-pksF-pksG-pksH-pksI-pksJ-pksL-pksM-pksN-pksR PubMed

    • Regulation

  • expressed during the transition from growth to stationary phase (AbrB, CodY) PubMed

    • Regulatory mechanism

  • AbrB: transcription repression PubMed
  • CodY: transcription activation PubMed

    • References

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