yodU [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

N-terminal part of the split gene spsM (together with ypqP), spore envelope polysaccharide biosynthesis, in B. subtilis 168 the gene is disrupted by the SP-beta prophage

locus: BSU19810

pI: 9.82

mw: 15.00 kDa

function: spore envelope polysaccharide biosynthesis

product: unknown

essential: no

synonyms: ypqP, spsM

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.8|Biosynthesis of legionaminic acid (for spore crust))]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.5|Newly identified sporulation proteins (based on transcription profiling)]

[SW|Categories] containing this gene/protein

• [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigK regulon], [SW|GerE regulon]

Gene

Coordinates on the chromosome (coding sequence): 2,151,626 -> 2,152,045

The protein

Paralogous protein(s)

• [protein|search|EpsC] (for SpsM)

[SW|Domains]

• SpsM: Polysacc_synt_2 domain (Pfam accession number, PF02719) in the 18–296-aa region [Pubmed|25299644]

[SW|Localization]

• secreted (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|yodU]'' [Pubmed|22383849]

[SW|Sigma factor]

• [protein|search|SigK] [Pubmed|25299644,15383836]

Regulation

• expressed late during [SW|sporulation] in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|25299644,15383836]

Regulatory mechanism

• [protein|search|GerE]: transcription activation [Pubmed|25299644,15383836]

References

• 25299644,15383836,25326298