SubtiBank SubtiBank
xylB
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xylB

xylulokinase
Locus
BSU_17610
Isoelectric point
6.46
Molecular weight
55.25 kDa
Protein length
499 aa Sequence Blast
Gene length
1500 bp Sequence Blast
Function
utilization of xylan and xylose
Product
xylulokinase
Essential
no
E.C.
2.7.1.17
Synonyms
yncA

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,893,396 → 1,894,895

The protein

Catalyzed reaction/ biological activity

  • ATP + D-xylulose --> ADP + D-xylulose 5-phosphate + H+ (according to UniProt)
  • Protein family

  • FGGY kinase family (according to UniProt)
  • Structure

  • 2NLX (from E. coli, 35% identity, 52% similarity) PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon
  • XylR: repression, PubMed, in XylR regulon
  • Regulation

  • carbon catabolite repression (CcpA) PubMed
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    Biological materials

    Mutant

  • GP1151 (del aphA3) available in Stülke lab
  • 1A719 (no resistance), PubMed, available at BGSC
  • BKE17610 (ΔxylB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTTTCACTCCTTGCCC, downstream forward: _UP4_TAATGATGTTATTGTCTGGA
  • BKK17610 (ΔxylB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATTTTTTCACTCCTTGCCC, downstream forward: _UP4_TAATGATGTTATTGTCTGGA
  • Labs working on this gene/protein

  • Wolfgang Hillen, Erlangen University, Germany Homepage
  • References

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