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yxdJ [2019-08-28 12:30:58]
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yxdJ [2019-08-28 12:30:58]

two-component response regulator (OmpR family), regulation of the ABC transporter YxdL-YxdM in response to the cationic antimicrobial peptide, LL-37
Locus
BSU_39660
Isoelectric point
4.94
Molecular weight
26.45 kDa
Protein length
229 aa Sequence Blast
Gene length
690 bp Sequence Blast
Function
resistance against toxic peptides
Product
two-component response regulator (OmpR family)
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Regulation of gene expression → Transcription factors and their control → Two-component system response regulators
  • Lifestyles → Coping with stress → Resistance against toxins/ antibiotics
  • Groups of genes → Phosphoproteins → Phosphorylation on an Asp residue

    • Gene

    Coordinates
    4,072,284 → 4,072,973

    The protein

    Protein family

  • OmpR family of two-component response regulators

    • Modification

  • phosphorylated by YxdK on an Asp residue

    • Structure

  • 5DCL (NisR from Streptococcus agalactiae, 41% identity)

    • Expression and Regulation

    Operons

    Genes
    yxdJ-yxdK
    Description
    PubMed
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    Biological materials

    Mutant

  • MGNA-B702 (yxdJ::erm), available at the NBRP B. subtilis, Japan
  • BKE39660 (ΔyxdJ::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAACTGAACCACTCCCGTT, downstream forward: _UP4_GGCTACCAGCTGAGGGCGCA
  • BKK39660 (ΔyxdJ::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAACTGAACCACTCCCGTT, downstream forward: _UP4_GGCTACCAGCTGAGGGCGCA

    • References

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