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manR [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]
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manR [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

transcriptional activator of the manP-manA-yjdF operon
Locus
BSU12000
Isoelectric point
8.04
Molecular weight
75.00 kDa
Function
regulation of mannose utilization
Product
transcriptional activator, PRD-type
Essential
no
Synonyms
yjdC
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of mannose
  • Information processing → Regulation of gene expression → Transcription factors and their control → PRD-type regulators
  • Groups of genes → Phosphoproteins → Phosphorylation on a His residue

    • Categories containing this gene/protein

  • utilization of specific carbon sources, transcription factors and their control, phosphoproteins

    • This gene is a member of the following regulons

  • CcpA regulon, ManR regulon

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,270,631 -> 1,272,577

    The protein

    Modification

  • phosphorylation by ManP inactivates ManR (in the absence of mannose), phosphorylation by [ptsH|search|HPr] stimluates ManR PubMed

    • Interactions

  • ManP-ManR PubMed
  • [ptsH|search|HPr]-ManR PubMed

    • Expression and Regulation

    Operon

  • manR PubMed

    • Sigma factor

  • SigA PubMed

    • Regulation

  • induced by mannose (ManR) PubMed
  • repressed by glucose (CcpA, ManR) PubMed

    • Regulatory mechanism

  • ManR: transcription activation in the presence of mannose and absence of glucose PubMed
  • CcpA: transcription repression PubMed

    • References

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