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mmgC [2018-02-13 15:44:06]
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mmgC [2018-02-13 15:44:06]

acyl-CoA dehydrogenase
Locus
BSU24150
Isoelectric point
8.52
Molecular weight
40.71 kDa
Protein length
378 aa Sequence Blast
Gene length
1134 bp Sequence Blast
Function
mother cell metabolism
Product
acyl-CoA dehydrogenase
Essential
no
Synonyms
yqiN
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Amino acid/ nitrogen metabolism → Utilization of amino acids → Utilization of branched-chain amino acids
  • Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other

    • Gene

    Coordinates
    2,510,806 → 2,511,945

    The protein

    Catalyzed reaction/ biological activity

  • Acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF (according to Swiss-Prot)

    • Protein family

  • acyl-CoA dehydrogenase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • YngJ, AcdA, FadE, YotC FadE(40.2%)

    • Structure

  • 3OWA (from B. anthracis, 39% identity, 55% similarity)
  • 4L1F (from Acidaminococcus Fermentans, 56% identity)

    • Expression and Regulation

    Operons

    Genes
    mmgA-mmgB-mmgC-mmgD-mmgE-mmgF
    Description
    PubMed

    Sigma factors

  • SigE: sigma factor, PubMed, in SigE regulon

    • Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon

    • Regulation

  • expressed early during sporulation in the mother cell (SigE) PubMed
  • strongly expressed during oligotrophic growth PubMed
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    Biological materials

    Mutant

  • BKE24150 (ΔmmgC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAACTCGGCCACCCCCGGAT, downstream forward: _UP4_TGATAGACAAAAAACGCAAA
  • BKK24150 (ΔmmgC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAACTCGGCCACCCCCGGAT, downstream forward: _UP4_TGATAGACAAAAAACGCAAA

    • References

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