iolS

similar to dehydrogenase, may be involved in myo-inositol catabolism

Locus: BSU_39780

Isoelectric point: 5.38

Molecular weight: 35.01 kDa

Protein length: 310 aa

Gene length: 933 bp

Function: unknown, may be involved in myo-inositol catabolism

Product: unknown

Essential: no

Synonyms: yxbF

Genomic Context

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Categories containing this gene/protein

• Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of inositol

Gene

Coordinates: 4,085,608 → 4,086,540

The protein

Protein family

• Aldo/keto reductase family (according to UniProt)

Paralogous protein(s)

• YhdN, YccK
• YqkF:

Structure

• 1PZ0 PubMed

Expression and Regulation

Operons

• Genes: iolR-iolS
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulatory mechanism

  • IolR: repression, PubMed, in IolR regulon

  Regulation

  • induced by inositol (IolR) PubMed

Biological materials

Mutant

• BKE39780 (ΔiolS::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGATCTGCCTCCTAGAAT, downstream forward: _UP4_TAAGAAGAAAACAGCCTTCT
• BKK39780 (ΔiolS::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGATCTGCCTCCTAGAAT, downstream forward: _UP4_TAAGAAGAAAACAGCCTTCT

Labs working on this gene/protein

• Yasutaro Fujita, University of Fukuyama, Japan
• [[Ken-ichi Yoshida]], Kobe University, Japan

References

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