SubtiBank SubtiBank
yaaO
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yaaO

similar to arginine decarboxylase, affects the level of Efp modification
Locus
BSU_00270
Isoelectric point
5.71
Molecular weight
53.00 kDa
Protein length
480 aa Sequence Blast
Gene length
1440 bp Sequence Blast
Function
control of Efp modification
Product
putative arginine decarboxylase
Essential
no
E.C.
4.1.1.19
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Translation → Translation factor modification and maturation
  • Information processing → Protein synthesis, modification and degradation → Protein modification → Protein modification/ other
  • Groups of genes → Poorly characterized/ putative enzymes

    • Gene

    Coordinates
    37,720 → 39,162

    Phenotypes of a mutant

  • inactivation suppresses the swarming defect of a ymfI mutant PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • the protein was reported to be involved in norspermidine production and biofilm disassembly PubMed; however, this is not the case PubMed and the original paper has been retracted

    • Protein family

  • Orn/Lys/Arg decarboxylase class-I family (together with SpeA) (according to UniProt)

    • Paralogous protein(s)

  • SpeA

    • Cofactors

  • PLP (according to UniProt)

    • Structure

  • 2X3L (from Staphylococcus aureus, 36% identity) PubMed

    • Expression and Regulation

    Operons

    Genes
    xpaC-yaaN-yaaO-tmk-darA-yaaR-holB-yaaT-yabA-trmN6-yazA-yabC
    Description
    PubMed
    view in new tab

    Genes
    xpaC-yaaN-yaaO
    Description
    PubMed

    Sigma factors

  • SigW: sigma factor, PubMed, in SigW regulon
  • SigK: sigma factor, PubMed, in SigK regulon

    • Regulation

  • expressed in stationary phase
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B896 (yaaO::erm), available at the NBRP B. subtilis, Japan
  • BKE00270 (ΔyaaO::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGAAAACAATCCTTTGAA, downstream forward: _UP4_GTTTATATAGAAGAGGAGAA
  • BKK00270 (ΔyaaO::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGAAAACAATCCTTTGAA, downstream forward: _UP4_GTTTATATAGAAGAGGAGAA

    • References

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