SubtiBank SubtiBank
ymcA [2019-09-20 18:07:50]
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ymcA [2019-09-20 18:07:50]

subunit of the regulatory iron-sulfur containing YmcA-YlbF-YaaT complex, required for RNase Y dependent maturation of polycistronic mRNAs, antagonist of biofilm repression by SinR, control of the phosphorelay
Locus
BSU_17020
Isoelectric point
5.09
Molecular weight
16.02 kDa
Protein length
143 aa Sequence Blast
Gene length
432 bp Sequence Blast
Function
control of RNase Y activity, see Targets of the Y complex
Product
subunit of the regulatory iron-sulfur containing YmcA-YlbF-YaaT complex
Essential
no
Synonyms
ricA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → RNA synthesis and degradation → RNases → Effectors of RNA degradation
  • Information processing → Regulation of gene expression → Transcription factors and their control → Control of transcription factor (other than two-component system)
  • Information processing → Regulation of gene expression → phosphorelay → Other protein controlling the activity of the phosphorelay
  • Lifestyles → Exponential and early post-exponential lifestyles → Biofilm formation
  • Lifestyles → Exponential and early post-exponential lifestyles → Biofilm formation → Other proteins required for biofilm formation
  • Lifestyles → Sporulation → phosphorelay → Other protein controlling the activity of the phosphorelay

    • Gene

    Coordinates
    1,774,374 → 1,774,805

    Phenotypes of a mutant

  • strongly reduced genetic competence, strongly reduced sporulation PubMed
  • defective in RNase Y-mediated maturation of polycistronic mRNAs, see Targets of the Y complex PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • the YmcA-YlbF-YaaT complex acts as specificity factor for RNase Y-dependent processing of polycistronic mRNAs, see Targets of the Y complex PubMed
  • the YmcA-YlbF-YaaT complex stimulates Spo0A phosphorylation in the phosphorelay PubMed

    • Structure

  • 2PIH

    • Localization

  • cytoplasm PubMed

    • Expression and Regulation

    Operons

    Genes
    ymcB-ymcA
    Description
    PubMed
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    Biological materials

    Mutant

  • BKE17020 (ΔymcA::erm trpC2) available at BGSC and in Jörg Stülke's lab, PubMed, upstream reverse: _UP1_GTCTTTTTTTGAGTAGAGCG, downstream forward: _UP4_TAAACACGGTGCCTTTACAG
  • BKK17020 (ΔymcA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_GTCTTTTTTTGAGTAGAGCG, downstream forward: _UP4_TAAACACGGTGCCTTTACAG

    • References

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