SubtiBank SubtiBank
ymcA [2018-05-30 18:21:47]
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ymcA [2018-05-30 18:21:47]

subunit of the regulatory iron-sulfur containing YmcA-YlbF-YaaT complex, required for RNase Y dependent maturation of polycistronic mRNAs, antagonist of biofilm repression by SinR, control of the phosphorelay
Locus
BSU17020
Isoelectric point
5.09
Molecular weight
16.02 kDa
Protein length
143 aa Sequence Blast
Gene length
429 bp Sequence Blast
Function
control of RNase Y activity
Product
subunit of the regulatory iron-sulfur containing YmcA-YlbF-YaaT complex
Essential
no
Synonyms
ricA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → RNA synthesis and degradation → RNases → Effectors of RNA degradation
  • Information processing → Regulation of gene expression → Transcription factors and their control → Control of transcription factor (other than two-component system)
  • Information processing → Regulation of gene expression → phosphorelay → Other protein controlling the activity of the phosphorelay
  • Lifestyles → Exponential and early post-exponential lifestyles → Biofilm formation
  • Lifestyles → Exponential and early post-exponential lifestyles → Biofilm formation → Other proteins required for biofilm formation
  • Lifestyles → Sporulation → phosphorelay → Other protein controlling the activity of the phosphorelay

    • Gene

    Coordinates
    1,774,374 → 1,774,805

    Phenotypes of a mutant

  • strongly reduced genetic competence, strongly reduced sporulation PubMed
  • defective in RNase Y-mediated maturation of polycistronic mRNAs PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • the YmcA-YlbF-YaaT complex acts as specificity factor for RNase Y-dependent processing of polycistronic mRNAs PubMed
  • the YmcA-YlbF-YaaT complex stimulates Spo0A phosphorylation in the phosphorelay PubMed

    • Structure

  • 2PIH

    • Localization

  • cytoplasm PubMed

    • Expression and Regulation

    Operons

    Genes
    ymcB-ymcA
    Description
    PubMed
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    Biological materials

    Mutant

  • BKE17020 (ΔymcA::erm trpC2) available at BGSC and in Jörg Stülke's lab, PubMed, upstream reverse: _UP1_GTCTTTTTTTGAGTAGAGCG, downstream forward: _UP4_TAAACACGGTGCCTTTACAG
  • BKK17020 (ΔymcA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_GTCTTTTTTTGAGTAGAGCG, downstream forward: _UP4_TAAACACGGTGCCTTTACAG

    • References

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