gerKA [Wed Jan 06 2016 13:28:56 GMT+0100 (CET)]

nutrient receptor

locus: BSU03700

pI: 5.00

mw: 60.00 kDa

function: germination response to the combination of glucose,
fructose, aspartate, and KCl

product: nutrient receptor

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.4|Germination] → [category|SW 4.2.4.1|Germinant receptors]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|germination], [SW|membrane proteins]

This gene is a member of the following [SW|regulons]

• [SW|SigG regulon], [SW|SpoVT regulon]

Gene

Coordinates on the chromosome (coding sequence): 420,110 -> 421,744

The protein

Protein family

• gerABKA family (according to Swiss-Prot)

[SW|Domains]

• contains multiple membrane-spanning domains [Pubmed|23335419]

[SW|Localization]

• outer surface of the inner spore membrane [Pubmed|23335419,21696470]

[SW|Interactions]

• [SW|GerKA]-[SW|GerKB]-[SW|GerKC] (tentative receptor complex) [Pubmed|21696470]
• [SW|GerKA] is part of the [SW|germinosome] in the spore inner membrane [Pubmed|21696470]

Additional information

• 700 molecules are present per spore [Pubmed|23749970]

Expression and Regulation

Operon

• ''[SW|gerKA]-[SW|gerKC]-[SW|gerKB]'' (according to [http://dbtbs.hgc.jp/COG/prom/gerKACB.html DBTBS])

[SW|Sigma factor]

• SigG [Pubmed|16707705]

Regulation

• expressed during sporulation ([protein|search|SigG], [SW|SpoVT]) [Pubmed|16707705]

Regulatory mechanism

• [SW|SpoVT]: transcription repression [Pubmed|16707705]

Additional information

• 700 molecules are present per spore [PubMed|23749970]

References

• 16707705,16352818,21696470,23335419,23396907,22343299,16740944,23749970,24752279