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uxaA [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]
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uxaA [Tue Dec 13 2016 11:16:32 GMT+0100 (CET)]

altronate hydrolase
Locus
BSU12390
Isoelectric point
5.78
Molecular weight
54.00 kDa
Function
hexuronate utilization
Product
altronate hydrolase
Essential
no
E.C.
4.2.1.7
Synonyms
yjmJ
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Carbon metabolism → Utilization of specific carbon sources → Utilization of hexuronate
  • Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other

    • Categories containing this gene/protein

  • utilization of specific carbon sources, sporulation proteins

    • This gene is a member of the following regulons

  • CcpA regulon, ExuR regulon, SigE regulon

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,311,319 -> 1,312,812

    The protein

    Catalyzed reaction/ biological activity

  • D-altronate = 2-dehydro-3-deoxy-D-gluconate + H2O (according to Swiss-Prot)

    • Protein family

  • uxaA family (according to Swiss-Prot)

    • Expression and Regulation

    Operon

  • uxaC-yjmB-yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA PubMed
  • yjmC-yjmD-uxuA-yjmF-exuT-exuR-uxaB-uxaA PubMed

    • Sigma factor

  • uxaC: SigA PubMed
  • yjmC: SigE PubMed

    • Regulation

  • repressed by glucose (CcpA) PubMed1 PubMed2
  • induced by galacturonate (ExuR) PubMed

    • Regulatory mechanism

  • CcpA: transcription repression PubMed1 PubMed2
  • ExuR: reanscription repression in the absence of inducer PubMed

    • References

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