SubtiBank SubtiBank
bmrA [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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bmrA [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

multidrug ABC transporter (ATP-binding protein)
locus
BSU34820
pI
6.00
mw
64.00 kDa
function
multiple antibiotic resistance
product
multidrug ABC transporter (ATP-binding protein)
essential
no
synonyms
yvcC

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.1|Efflux of antibiotics]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|resistance against toxins/ antibiotics], [SW|membrane proteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,577,745 -> 3,579,514

    The protein

    [SW|Domains]

  • has both a membrane-spanning and an ATP-binding domain [Pubmed|10092453]
  • [SW|Localization]

  • membrane [Pubmed|10092453]
  • Expression and Regulation

    [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|21077936]
  • Regulation

  • constitutively expressed [Pubmed|21077936]
  • Additional information

  • half-life of the mRNA: 1.5 min [PubMed|21077936]
  • References

  • 16107340,15182191,15766260,16405427,12968023,10092453,18215075,12225846,20544182,11827477,21077936,21336797,21483854,27570617