rsiV [Tue Dec 13 2016 11:16:35 GMT+0100 (CET)]

anti-sigma factor to SigV

Locus: BSU27130

Isoelectric point: 5.00

Molecular weight: 32.00 kDa

Function: control of SigV activity

Product: anti-sigma factor to SigV

Essential: no

Synonyms: yrhM

Genomic Context

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Categories containing this gene/protein

• Information processing → Regulation of gene expression → Sigma factors and their control → Control of sigma factors
• Lifestyles → Coping with stress → Cell envelope stress proteins (controlled by SigM, V, W, X, Y)
• Groups of genes → Membrane proteins

Categories containing this gene/protein

• sigma factors and their control, cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins

This gene is a member of the following regulons

• SigV regulon

Gene

Coordinates on the chromosome (coding sequence): 2,770,350 -> 2,771,207

The protein

Catalyzed reaction/ biological activity

• binds and thus inactivates SigV

Effectors of protein activity

• RsiV directly binds lysozyme PubMed
• upon exposure to lysozyme, the extracellular domain of RsiV is cleaved off by SipS (between A66 and M67), subsequently the N-terminal part of the protein is subject to intramemrane proteolysis by RasP PubMed

Localization

• membrane PubMed

Interactions

• SigV-RsiV, this interaction inhibits the activity of SigV PubMed
• RasP-RsiV, degradation of RsiV PubMed

Expression and Regulation

Operon

• sigV-rsiV-oatA-yrhK PubMed

Sigma factor

• SigV PubMed

Regulation

• induced by lysozyme (SigV) PubMed

References

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