anti-sigma factor to SigV
function
control of SigV activity
product
anti-sigma factor to SigV
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|sigma factors and their control], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigV regulon]Gene
Coordinates on the chromosome (coding sequence)
2,770,350 -> 2,771,207
The protein
Catalyzed reaction/ biological activity
binds and thus inactivates [protein|search|SigV]Effectors of protein activity
RsiV directly binds lysozyme [Pubmed|25275625]upon exposure to lysozyme, the extracellular domain of [protein|search|RsiV] is cleaved off by [protein|search|SipS] (between A66 and M67), subsequently the N-terminal part of the protein is subject to intramemrane proteolysis by [protein|search|RasP] [Pubmed|25275625,23687273][SW|Localization]
membrane [Pubmed|23687273][SW|Interactions]
[protein|search|SigV]-[protein|search|RsiV], this interaction inhibits the activity of [protein|search|SigV] [Pubmed|23687273][protein|search|RasP]-[protein|search|RsiV], degradation of [protein|search|RsiV] [Pubmed|23687273]Expression and Regulation
Operon
''[protein|search|sigV]-[protein|search|rsiV]-[protein|search|oatA]-[protein|search|yrhK]'' [Pubmed|21856855][SW|Sigma factor]
[protein|search|SigV] [Pubmed|21856855]Regulation
induced by lysozyme ([protein|search|SigV]) [Pubmed|21856855]References
14993308,16274938,20817771,23687273,25275625,26399770 
