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glpK [2017-07-10 13:54:11]
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glpK [2017-07-10 13:54:11]

glycerol kinase
Locus
BSU09290
Isoelectric point
4.99
Molecular weight
54.91 kDa
Protein length
496 aa Sequence Blast
Gene length
1488 bp Sequence Blast
Function
glycerol utilization
Product
glycerol kinase
Essential
no
E.C.
2.7.1.30
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
1,003,344 → 1,004,834

The protein

Catalyzed reaction/ biological activity

  • ATP + glycerol = ADP + sn-glycerol 3-phosphate (according to Swiss-Prot)
  • Protein family

  • FGGY kinase family (according to Swiss-Prot)
  • Modification

  • phosphorylation (His230) (according to swissprot
  • Structure

  • 3H46 (from Enterococcus casseliflavus, complex with glycerol) PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • CcpA: repression, PubMed, in CcpA regulon
  • GlpP: antitermination, /antitermination via GlpP-dependent RNA switch, in GlpP regulon
  • AbrB: activation, PubMed, in AbrB regulon
  • ResD: repression, PubMed, in ResD regulon
  • Regulation

  • induction by glycerol (GlpP) PubMed
  • repressed under anaerobic conditions (ResD) PubMed
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    Biological materials

    Mutant

  • BKE09290 (glpK::ermC) (available at the BGSC and in Jörg Stülke's lab) PubMed
  • GP1865 (glpK::ermC) (available in Jörg Stülke's lab)
  • Labs working on this gene/protein

  • Josef Deutscher, Paris-Grignon, France
  • References

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