padC

phenolic acid decarboxylase

Locus: BSU_34400

Isoelectric point: 4.87

Molecular weight: 18.93 kDa

Protein length: 161 aa

Gene length: 486 bp

Function: resistance to salicylic acid

Product: phenolic acid decarboxylase

Essential: no

Synonyms: pad,yveH

Genomic Context

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Categories containing this gene/protein

• Lifestyles → Coping with stress → Resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)

Gene

Coordinates: 3,532,325 → 3,532,810

The protein

Catalyzed reaction/ biological activity

• conversion of ferulic acid to 4-vinylguaiacol PubMed
• H⁺ + trans-4-coumarate --> 4-hydroxystyrene + CO₂ (according to UniProt)
• H⁺ + trans-cinnamate --> CO₂ + styrene (according to UniProt)
• H⁺ + trans-ferulate --> 2-methoxy-4-vinylphenol + CO₂ (according to UniProt)

Protein family

• padC family (single member, according to UniProt)

Structure

• 2P8G

Expression and Regulation

Operons

• Genes: yveF-yveG-padC
  Description: PubMed

  Regulatory mechanism

  • PadR: repression, PubMed, in PadR regulon

  Regulation

  • induced by phenolic acid (PadR) PubMed

Biological materials

Mutant

• BKE34400 (ΔpadC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTTACACACTCTCCTTA, downstream forward: _UP4_TAATAAACATAAAAACCCGG
• BKK34400 (ΔpadC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCTTACACACTCTCCTTA, downstream forward: _UP4_TAATAAACATAAAAACCCGG

References

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