cotU [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

spore coat protein

locus: BSU17670

pI: 6.00

mw: 11.00 kDa

function: resistance of the spore

product: spore coat protein

essential: no

synonyms: ynzH

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.1|Spore coat proteins] → [category|SW 4.2.1.1.7|Class VI]

[SW|Categories] containing this gene/protein

• [SW|sporulation proteins]

This gene is a member of the following [SW|regulons]

• [SW|GerE regulon], [SW|GerR regulon], [SW|SigK regulon]

Gene

Coordinates on the chromosome (coding sequence): 1,901,117 -> 1,901,377

The protein

Paralogous protein(s)

• [SW|CotC]

[SW|Localization]

• outer spore coat, localization depends on [protein|search|CotE] [Pubmed|22171814]
• the [protein|search|CotC]-[protein|search|CotU] complex assembles around the forming spore [Pubmed|18065538]

[SW|Interactions]

• [protein|search|CotC]-[protein|search|CotU] [Pubmed|18065538], [protein|search|CotE]-[protein|search|CotU] [Pubmed|20023017]

Expression and Regulation

Operon

• ''cotU'' [Pubmed|22383849]

[SW|Sigma factor]

• [protein|search|SigK] [Pubmed|18065538]

Regulation

• expressed late during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|18065538]

Regulatory mechanism

• [protein|search|GerE]: transcription activation [Pubmed|18065538]
• [protein|search|GerR]: transcription repression [Pubmed|20435725]

References

Reviews

• 27227299

Original Publications

• 18065538,12562816,20023017,20435725,22171814,26953338