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resE [Fri Nov 13 2015 17:35:38 GMT+0100 (CET)]
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resE [Fri Nov 13 2015 17:35:38 GMT+0100 (CET)]

two-component sensor kinase, regulation of aerobic and anaerobic respiration
locus
BSU23110
pI
5.00
mw
66.00 kDa
function
regulation of aerobic and anaerobic respiration
product
two-component sensor kinase
essential
no
synonyms
ypxE
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.1|Regulators of electron transport]
  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]

    • [SW|Categories] containing this gene/protein

  • [SW|regulators of electron transport], [SW|protein modification], [SW|transcription factors and their control], [SW|membrane proteins], [SW|phosphoproteins]

    • This gene is a member of the following [SW|regulons]

  • [SW|CcpA regulon], [SW|PhoP regulon], [SW|ResD regulon]

    • Gene

    Coordinates on the chromosome (coding sequence)
    2,415,415 -> 2,417,184

    The protein

    Catalyzed reaction/ biological activity

  • autophosphorylation, phosphorylation of [protein|search|ResD]

    • [SW|Domains]

  • two transmembrane segments
  • [SW|PAS domain]
  • C-terminal histidine phosphotransferase domain

    • Modification

  • autophosphorylation on a His residue

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • [SW|Interactions]

  • [protein|search|ResE]-[protein|search|ResD]
  • [protein|search|FloT]-[protein|search|ResE] [Pubmed|26297017,25909364]

    • Expression and Regulation

    Operon

  • ''[protein|search|resA]-[protein|search|resB]-[protein|search|resC]-[protein|search|resD]-[protein|search|resE]'' [Pubmed|8631715]
  • ''[protein|search|resD]-[protein|search|resE]'' [Pubmed|8631715]

    • [SW|Sigma factor]

  • ''[protein|search|resA]'': [protein|search|SigA] [Pubmed|8631715]
  • ''[protein|search|resD]'': [protein|search|SigA] [Pubmed|8631715]

    • Regulation

  • expressed under anaerobic conditions ([protein|search|ResD]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8631715,11222591 PubMed]
  • expressed under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|9988472]
  • repressed by glucose ([protein|search|CcpA]) [Pubmed|16825793]

    • Regulatory mechanism

  • [protein|search|ResD]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8631715,11222591 PubMed]
  • [protein|search|PhoP]: transcription activation [Pubmed|9988472]
  • [protein|search|CcpA]: transcription repression [Pubmed|16825793]

    • References

    Reviews

  • 23046954

    • Original publications

  • 16885456,8631715,10094672,8682783,9352926,8631715,11222591,9988472,16825793,26297017,25909364