RNA-binding regulatory protein, negative effector of asymetric septation at the onset of sporulation
function
cell division, control of sporulation initiation
product
negative effector of asymetric septation
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes][category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.2|RNA chaperones][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.3|Sporulation/ other][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue][SW|Categories] containing this gene/protein
[SW|cell division], [SW|sporulation/ other], [SW|phosphoproteins]This gene is a member of the following [SW|regulons]
[SW|AbrB regulon], [SW|SigH regulon], [SW|SinR regulon]Gene
Coordinates on the chromosome (coding sequence)
55,866 -> 56,159
The protein
Protein family
spoVG family (according to Swiss-Prot)Modification
phosphorylation on (Ser-66 OR Ser-67 OR Thr-68) [Pubmed|17218307]Structure
[PDB|2IA9]Additional information
subject to Clp-dependent proteolysis upon glucose starvation [PubMed|17981983]Expression and Regulation
Operon
''spoVG'' [Pubmed|408013][SW|Sigma factor]
[protein|search|SigH] [Pubmed|408013]Regulation
repressed by [protein|search|SinR] [Pubmed|16430695]repressed during logrithmic growth ([protein|search|AbrB]) [Pubmed|2437099]Regulatory mechanism
[protein|search|SinR]: transcription repression [Pubmed|16430695][protein|search|AbrB]: transcription repression [Pubmed|2437099]Additional information
subject to Clp-dependent proteolysis upon glucose starvation [PubMed|17981983]Biological materials
Mutant
GP2109 (''[protein|search|spoVG]''::''tet'', available in [SW|Jörg Stülke]'s lab)References
408013,1850083,16430695,6405278,6411929,10348850,7559352,8419299,3100810,2437099,17218307,20803133,27048798 
