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sufC [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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sufC [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

ABC transporter (ATP-binding protein), synthesis of Fe-S clusters
locus
BSU32710
pI
4.00
mw
28.00 kDa
function
synthesis of Fe-S clusters
product
ABC transporter (ATP-binding protein)
essential
yes
synonyms
yurY

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.3|Regulatory ABC transporters]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.3|Biosynthesis of iron-sulfur clusters]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.8|Phosphorylation on either a Ser, Thr or Tyr residue]
  • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|iron metabolism], [SW|essential genes], [SW|phosphoproteins], [SW|most abundant proteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,359,995 -> 3,360,780

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Protein family

  • Ycf16 subfamily (according to Swiss-Prot)
  • Modification

  • phosphorylated on ser/ thr/ tyr [Pubmed|16493705]
  • Structure

  • [PDB|5AWF] (from ''E. coli'', the [SW|SufB]-[SW|SufC]-[SW|SufD] complex, 51% identity) [Pubmed|26472926]
  • [SW|Interactions]

  • [SW|SufB]-[SW|SufC]2-[SW|SufD] [Pubmed|26472926]
  • Expression and Regulation

    Operon

  • ''[protein|search|sufC]-[protein|search|sufD]-[protein|search|sufS]-[protein|search|sufU]-[protein|search|sufB]'' [Pubmed|22383849]
  • Additional information

  • belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]
  • Biological materials

    two-hybrid system

  • ''B. pertussis'' adenylate cyclase-based bacterial two hybrid system ([SW|BACTH]), available in [SW|Jörg Stülke]'s lab
  • References

  • 10092453,20097860,16493705,22383849,15378759,26472926,27179343