lichenan-specific phosphotransferase system, EIIA component of the PTS
function
lichenan uptake and phosphorylation
product
lichenan-specific phosphotransferase system,
EIIA component
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.2|Phosphotransferase system] → [category|SW 1.2.2.2|Sugar specific PTS proteins][category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.27|Utilization of other polymeric carbohydrates][category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue][SW|Categories] containing this gene/protein
[SW|phosphotransferase systems], [SW|utilization of specific carbon sources], [SW|phosphoproteins], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|CcpA regulon], [SW|LicR regulon]Gene
Coordinates on the chromosome (coding sequence)
3,959,841 -> 3,960,173
The protein
Catalyzed reaction/ biological activity
Protein EIIA N(pi)-phospho-L-histidine protein EIIB = protein EIIA protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot) Protein family
[SW|PTS] permease, lactose permease (Lac) family [Pubmed|10627040]Structure
[PDB|3K1S] (IIA(Cel) from ''B. anthracis'', 42% identity)[SW|Localization]
cytoplasm (according to Swiss-Prot)[SW|Interactions]
[protein|search|LicA]-[PtsH|search|HPr], [protein|search|LicA]-[protein|search|LicB]Expression and Regulation
Operon
''[protein|search|licB]-[protein|search|licC]-[protein|search|licA]-[protein|search|licH]'' [Pubmed|8990303][SW|Sigma factor]
[protein|search|SigA] [Pubmed|8990303]Regulation
carbon catabolite repression ([protein|search|CcpA]) [Pubmed|8990303]induction by oligomeric ß-glucosides ([protein|search|LicR])[Pubmed|8990303]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|8990303][protein|search|LicR]: transcription activation [Pubmed|8990303]References
19087206,8990303,16872404,10438772,10627040,8990303 
