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yfiC [2018-05-04 17:09:12]
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yfiC [2018-05-04 17:09:12]

similar to [SW|ABC transporter] (ATP-binding protein)
locus
BSU08220
pI
9.62
mw
67.22 kDa
protein length
604 aa Sequence Blast
gene length
1812 bp Sequence Blast
function
unknown
product
[SW|ABC transporter] (ATP-binding protein)
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.6|Exporters of unknown function]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    895,619 → 897,433

    The protein

    Protein family

  • [SW|ABC transporter] domain (according to Swiss-Prot)

    • [SW|Domains]

  • has both a membrane-spanning and an ATP-binding domain [Pubmed|10092453]

    • Structure

  • [PDB|3QF4] ([protein|288CA73D93B1E5106E1C6CE5E7E2E8BE2A6BD3F3|YfiB]-[protein|E85814EDF232D21A42380D559EAD2CDFB41F19DB|YfiC] complex from Thermotoga maritima, 48% identity) [pubmed|22447242]

    • [SW|Localization]

  • cell membrane [Pubmed|10092453]

    • Expression and Regulation

    Operons

    genes
    [gene|288CA73D93B1E5106E1C6CE5E7E2E8BE2A6BD3F3|yfiB]-[gene|E85814EDF232D21A42380D559EAD2CDFB41F19DB|yfiC]
    description
    [pubmed|22383849]
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    Biological materials

    Mutant

  • MGNA-C293 (yfiC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2291 NBRP B. subtilis, Japan]
  • BKE08220 (Δ[gene|E85814EDF232D21A42380D559EAD2CDFB41F19DB|yfiC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE08220 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGGAAAGGCTTGCGGATGT, downstream forward: _UP4_TAGACCTTTGTCCTGCACAG
  • BKK08220 (Δ[gene|E85814EDF232D21A42380D559EAD2CDFB41F19DB|yfiC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK08220 BGSC], [Pubmed|28189581], upstream reverse: _UP1_TTGGAAAGGCTTGCGGATGT, downstream forward: _UP4_TAGACCTTTGTCCTGCACAG

    • References

  • 10092453,22447242