bsrB

6S RNA, important for timing of [SW|sporulation]

locus: BSU_misc_RNA_32

pI: 0.00

mw: 0.00 kDa

gene length: 187 bp

function: antagonist of [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]

product: 6S RNA

essential: no

synonyms: 6S-2 RNA

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]
• [category|SW 6|Groups of genes] → [category|SW 6.9|NcRNA] → [category|SW 6.9.1|6S RNA]

Gene

Phenotypes of a mutant

• increased [SW|biofilm formation] (in undomesticated strains) [pubmed|32862759]

RNA

Catalyzed reaction/ biological activity

• binds to [SW|RNA polymerase] in [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]-dependent manner to repress transcription from a subgroup of promoters [pubmed|16336121]

Structure

• [PDB|5VT0] (E. coli 6S RNA in complex with [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]-containing [SW|RNA polymerase] holoenzyme) [pubmed|28988932]

The protein

Structure

• [PDB|5VT0] (E. coli 6S RNA in complex with [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]-containing [SW|RNA polymerase] holoenzyme) [pubmed|28988932]

Expression and Regulation

Operons

• genes: [gene|E85341621B3835F63F07C506E08B73A92E588B1F|bsrB]
  description: [Pubmed|22383849]

• genes: [gene|E85341621B3835F63F07C506E08B73A92E588B1F|bsrB]-[gene|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|recQ]-[gene|BEBA71A2EF56DAEAF80924856DA68124805BB158|yocH]
  description: [Pubmed|22383849]

References

Reviews

• 17714443,16336121,24786589,29916345

Research papers

• 21881410,24464747,25483037,25576829,26873600,28988932,32862759