RNA polymerase ECF-type sigma factor SigX, required for resistance against cationic antimicrobial peptides
function
resistance to cationic antimcrobial peptides
product
RNA polymerase ECF-type sigma factor SigX
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors][category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|transcription], [SW|sigma factors and their control], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigX regulon], [SW|YvrHb regulon]Gene
Coordinates on the chromosome (coding sequence)
2,414,627 -> 2,415,211
The protein
Protein family
ECF subfamily (according to Swiss-Prot)[SW|Localization]
cell membrane (according to Swiss-Prot)[SW|Interactions]
[protein|search|RsiX]-[protein|search|SigX] [Pubmed|9393439][protein|search|SigX]-[protein|search|RpoB]-[protein|search|RpoC]Additional information
Expression of the [SW|SigX regulon] in increased in ''[protein|search|ugtP]'' mutants [Pubmed|22362028]Expression and Regulation
Operon
''[protein|search|sigX]-[protein|search|rsiX]'' [Pubmed|7934830][SW|Sigma factor]
[protein|search|SigA] [Pubmed|9636707], [protein|search|SigX] [Pubmed|9636707]Regulation
induced in the stationary phase due to the internal production of toxic peptides ([SW|SdpC], [SW|SkfA]) [Pubmed|26364265]Regulatory mechanism
activated by [SW|YvrHb] [Pubmed|16306698]Biological materials
Mutant
MGNA-A179 (sigX::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/179 NBRP B. subtilis, Japan]1A901 ( ''sigX''::''spec''), [Pubmed| ], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A901&Search=1A901 BGSC]References
Reviews
The [SW|SigX regulon]
9683469,17675383,10960106 Other original publications
11222589,9139908,14993308,12399481,14762009,19047346,14651641,19465659,9636707,16306698,7934830,19767430,9393439,22362028,23103977,20817771,26364265,27137497 
