rplL [2019-07-08 10:38:55]

ribosomal protein L12

Locus: BSU01050

Isoelectric point: 4.36

Molecular weight: 12.61 kDa

Protein length: 123 aa

Gene length: 372 bp

Function: translation

Product: ribosomal protein L12 (BL9)

Essential: yes

Synonyms

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Translation → Ribosomal proteins
• Groups of genes → Essential genes

Gene

Coordinates: 120,607 → 120,978

Phenotypes of a mutant

• essential PubMed

The protein

Protein family

• Bacterial ribosomal protein bL12 family (single member, according to UniProt)

Structure

• 3J9W (the ribosome) PubMed

Localization

• ribosome (according to UniProt)

Additional information

• belongs to the 100 most abundant proteins PubMed

Expression and Regulation

Operons

• Genes: rplJ-rplL
  Description: PubMed

  Regulatory mechanism

  • RplJ: termination, at excess of the RplJ-RplL₄ complex, in RplJ regulon
  • stringent response: negative regulation, in stringent response
  • RplL: termination, at excess of the RplJ-RplL₄ complex, in RplL regulon

  Regulation

  • termination/ antitermination (L10-L12₄ complex) PubMed

• Genes: rplK-rplA-BSU_misc_RNA_3-rplJ-rplL
  Description: PubMed

  Regulatory mechanism

  • stringent response: negative regulation, PubMed, in stringent response

  Regulation

  • RelA dependent downregulation (Class I) during stringent response PubMed

References

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