recQ [2018-02-12 16:20:20]

ATP-dependent DNA helicase, acts together with [protein|BA755FA1CB1E0C006E9A23489A7C8997141AA498|RecJ]

locus: BSU19220

pI: 5.92

mw: 67.18 kDa

protein length: 591 aa

gene length: 1773 bp

function: DNA repair

product: ATP-dependent DNA helicase

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.6|DNA repair/ recombination/ based on similarity]

Gene

Coordinates: 2,094,010 → 2,095,785

The protein

Paralogous protein(s)

• [protein|4A4FCD876C3CA1D821792803CA2A0CB2E97D3F5E|RecS]

Structure

• [PDB|4O3M] (Bloom's syndrome helicase, 35% identity)

Expression and Regulation

Operons

• genes: [gene|E85341621B3835F63F07C506E08B73A92E588B1F|bsrB]-[gene|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|recQ]-[gene|BEBA71A2EF56DAEAF80924856DA68124805BB158|yocH]
  description: [Pubmed|22383849]

Biological materials

Mutant

• MGNA-B414 (yocI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1413 NBRP B. subtilis, Japan]
• BKE19220 (Δ[gene|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|recQ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE19220 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAACGTGTAAACCTCGCT, downstream forward: _UP4_TAAAAAAACAGAAAAACAAT
• BKK19220 (Δ[gene|E6EA8098E37A4A2F7370920AC1A500EE4319AAA2|recQ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK19220 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAACGTGTAAACCTCGCT, downstream forward: _UP4_TAAAAAAACAGAAAAACAAT

References

Reviews

• 22933559

Original publications

• 25246477