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ywrB
subunit of chromate exporter (with [protein|70CC5C9BCC676AB89C0BF80686BD98BA08FAE648|YwrA])
function
chromate detoxification
product
chromate exporter
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.11|Other exporters][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.11|Resistance against toxic metals][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
3,721,415 → 3,722,008
The protein
Protein family
chromate ion transporter (CHR) (TC 2.A.51) family (with [protein|70CC5C9BCC676AB89C0BF80686BD98BA08FAE648|YwrA], according to UniProt)[SW|Localization]
cell membrane [Pubmed|22900751]Expression and Regulation
Operons
genes
[gene|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|chrS]-[gene|E63704C51B53F05BAD9B35D3B6874DB9231B6D24|ywrB]-[gene|70CC5C9BCC676AB89C0BF80686BD98BA08FAE648|ywrA]
description
[Pubmed|22383849]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|23989926], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|ChrS]: repression, [Pubmed|23989926], in [regulon|C0BEEAD315077FE3D0D061D1D447D03E6CB48D6A|ChrS regulon]view in new tabBiological materials
Mutant
MGNA-A570 (ywrB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/570 NBRP B. subtilis, Japan]BKE36120 (Δ[gene|E63704C51B53F05BAD9B35D3B6874DB9231B6D24|ywrB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE36120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGTTTCTCTCCTTTAC, downstream forward: _UP4_TCATGATATCGATCTATTTABKK36120 (Δ[gene|E63704C51B53F05BAD9B35D3B6874DB9231B6D24|ywrB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK36120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGTTTCTCTCCTTTAC, downstream forward: _UP4_TCATGATATCGATCTATTTAReferences
19581367,22383849,22900751,23989926