tatCY

component of the TatAY-TatCY twin-arginine translocase

Locus: BSU_05990

Isoelectric point: 9.69

Molecular weight: 28.91 kDa

Protein length: 254 aa

Gene length: 765 bp

Function: TAT protein secretion

Product: component of the twin-arginine translocation pathway

Essential: no

Synonyms: ydiJ

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Protein secretion
• Groups of genes → Membrane proteins

Gene

Coordinates: 647,940 → 648,704

The protein

Catalyzed reaction/ biological activity

• secretion of EfeB and YkuE
• delivers QcrA to the membrane PubMed

Protein family

• tatC family (with TatCD, according to UniProt)

Paralogous protein(s)

• TatCD

Structure

• 4HTT (from Aquifex aeolicus, 35% identity) PubMed

Localization

• cell membrane (according to Swiss-Prot), Polar (Septum) PubMed

Additional information

• TatAY-TatCY-dependent export of YkuE and EfeB requires a functional WprA PubMed

Expression and Regulation

Operons

• Genes: tatAY-tatCY
  Description: PubMed

  Regulation

  • constitutitvely expressed PubMed

• Genes: ydiG-rex-tatAY-tatCY
  Description: PubMed

  Regulation

  • constitutitvely expressed PubMed
  • the mRNA is processed between rex and tatAY by RNase Y, this requires the YmcA-YlbF-YaaT complex PubMed

Biological materials

Mutant

• BKE05990 (ΔtatCY::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCCTAACTTACTGATCTT, downstream forward: _UP4_TAATAAAAAATCCATTTCTC
• BKK05990 (ΔtatCY::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATCCTAACTTACTGATCTT, downstream forward: _UP4_TAATAAAAAATCCATTTCTC

Labs working on this gene/protein

• Jan Maarten van Dijl, University of Groningen, The Netherlands, Homepage

References

Reviews

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Research papers

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Original publications

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