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lutP [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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lutP [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

lactate permease
locus
BSU34190
pI
9.00
mw
59.00 kDa
function
lactate uptake
product
lactate permease
essential
no
synonyms
yvfH

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.4|Transporter for organic acids]
  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.1|Utilization of organic acids]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|transporters/ other], [SW|utilization of specific carbon sources], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|ComA regulon], [SW|LutR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,510,780 -> 3,512,471

    Phenotypes of a mutant

  • poor growth with lactate as single carbon source [Pubmed|19201793]
  • The protein

    Catalyzed reaction/ biological activity

  • lactate uptake [Pubmed|19201793]
  • Protein family

  • lactate permease family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|LctP]
  • [SW|Localization]

  • membrane [Pubmed|18763711]
  • Expression and Regulation

    Operon

  • ''[SW|lutP]'' [Pubmed|22383849]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|25031425]
  • Regulation

  • expressed at high cell density ([protein|search|ComA]) [Pubmed|16091051]
  • Regulatory mechanism

  • [protein|search|ComA]: transcription activation ([protein|search|ComA]) [Pubmed|16091051]
  • Labs working on this gene/protein

  • [SW|Richard Losick], Harvard Univ., Cambridge, USA [http://www.mcb.harvard.edu/Losick/ homepage]
  • References

  • 19201793,18763711,16091051,25031425,26582911