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yhxA [2017-8-11 16:0:3]
similar to adenosylmethionine-8-amino-7-oxononanoate aminotransferase
Genomic Context
categories
[category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]Gene
Coordinates
1,000,364 → 1,001,716
The protein
Protein family
class-III pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)Paralogous protein(s)
[protein|13DC4296015A28975BC7697F134FB6ECD6B11489|YodT] (34%), [protein|68C86FED3575B864C576DFB73FE7B5BF83994D1F|BioA] (33,6%), [protein|4E1FD02C6FE4103E3B4942BF5221C062CB8D0B9B|GabT] (32.8%)Structure
[PDB|3N5M] (from ''Bacillus Anthracis'', 64% identity)Additional information
subject to Clp-dependent proteolysis upon glucose starvation [Pubmed|17981983]Expression and Regulation
Operons
genes
[gene|E5F6DF14A4C01B2C90F70E37908D3697BC1B5FEF|yhxA]-[gene|38767691AE7E09F46B9E97A60BF5358C1876EDF8|glpP]
description
[Pubmed|2127799]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|21925382], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]additional information
half-life of the mRNA: 3.7 min [PubMed|21925382]half-life of the mRNA: 3.7 min [PubMed|21925382]view in new tabBiological materials
Mutant
MGNA-B475 (yhxA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1474 NBRP B. subtilis, Japan]References
17981983,2127799,21925382