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hemH [Wed Jan 20 2016 14:31:04 GMT+0100 (CET)]
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hemH [Wed Jan 20 2016 14:31:04 GMT+0100 (CET)]

ferrochelatase, catalyzes the final step of heme b biosynthesis
Locus
BSU10130
Isoelectric point
4.00
Molecular weight
35.00 kDa
Function
heme biosynthesis
Product
ferrochelatase
Essential
no
Synonyms
hemF
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of heme/ siroheme

    • Categories containing this gene/protein

  • biosynthesis of cofactors

    • Gene

    Coordinates on the chromosome (coding sequence)
    1,087,250 -> 1,088,182

    The protein

    Catalyzed reaction/ biological activity

  • insertion of Fe(2) into protoporphyrin IX

    • Protein family

  • ferrochelatase family (according to Swiss-Prot)

    • Structure

  • 2HK6 (complex with iron), 1AK1

    • Localization

  • cytoplasm (according to Swiss-Prot)

    • Interactions

  • (Fra)-HemH, requires iron, Kd of 1.63 ± 0.02 μM PubMed

    • Expression and Regulation

    Operon

  • hemE-hemH-hemY PubMed

    • References

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