sulphur N-acetylase, required for the conversion of S-methyl-cysteine to cysteine
function
utilization of S-methyl-cysteine
product
sulphur N-acetylase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism] → [category|SW 2.6.4.1|Conversion of S-methyl cysteine to cysteine][SW|Categories] containing this gene/protein
[SW|sulfur metabolism]This gene is a member of the following [SW|regulons]
[SW|CymR regulon], [SW|AscR regulon]Gene
Coordinates on the chromosome (coding sequence)
3,008,249 -> 3,008,785
Phenotypes of a mutant
reduced growth with S-methyl cysteine [Pubmed|23944997]the ''[protein|search|snaA] [protein|search|snaB]'' double mutant does not grow with S-methyl cysteine [Pubmed|23944997]The protein
Catalyzed reaction/ biological activity
N-acetylation of the amino group of S-methyl cysteine [Pubmed|23944997]Protein family
acetyltransferase family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|SnaB]Expression and Regulation
Operon
''[protein|search|snaA]-[protein|search|tcyJ]-[protein|search|tcyK]-[protein|search|tcyL]-[protein|search|tcyM]-[protein|search|tcyN]-[protein|search|cmoO]-[protein|search|cmoI]-[protein|search|cmoJ]-[protein|search|ribR]-[protein|search|sndA]-[protein|search|ytnM]'' [Pubmed|15668000][SW|Sigma factor]
[protein|search|SigA] [Pubmed|15272571]Regulation
repressed in the presence of cysteine ([protein|search|CymR]) [Pubmed|16109943]induced in the presence of S-methyl-cysteine ([protein|search|AscR]) [Pubmed|23944997]Regulatory mechanism
[protein|search|CymR]: transcription repression [Pubmed|16109943][protein|search|AscR]: transcription activation [Pubmed|16109943]References
15937167,16109943,15668000,11390694,23944997 
