ggaA

galactosamine-containing minor teichoic acid biosynthesis

Locus: BSU_35690

Isoelectric point: 9.06

Molecular weight: 52.98 kDa

Protein length: 446 aa

Gene length: 1341 bp

Function: biosynthesis of teichoic acid

Product: unknown

Essential: no

Synonyms

Genomic Context

Loading

Categories containing this gene/protein

• Cellular processes → Cell envelope and cell division → Cell wall synthesis → Biosynthesis of teichoic acid
• Metabolism → Additional metabolic pathways → Biosynthesis of cell wall components → Biosynthesis of teichoic acid
• Groups of genes → Phosphoproteins → Phosphorylation on an Arg residue

Gene

Coordinates: 3,670,035 → 3,671,375

The protein

Protein family

• glycosyltransferase 2 family (according to UniProt)

Modification

• phosphorylated on Arg-85 PubMed

Structure

• 5HEA (from Streptococcus parasanguinis,N-terminal domain, 32% identity)

Expression and Regulation

Operons

• Genes: ggaA-ggaB
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Additional information

  • an antisense RNA is predicted for ggaA PubMed
  • PhoP∼P binds to the promoter region, but regulation has not been explored PubMed

Biological materials

Mutant

• BKE35690 (ΔggaA::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTTTGTACCTCTTTATT, downstream forward: _UP4_TAAGGAATGCTTTTCATACA
• BKK35690 (ΔggaA::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATGTTTGTACCTCTTTATT, downstream forward: _UP4_TAAGGAATGCTTTTCATACA

References

Loading