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ftsX [Mon Aug 31 2015 13:57:03 GMT+0200 (CEST)]
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ftsX [Mon Aug 31 2015 13:57:03 GMT+0200 (CEST)]

ABC transporter (membrane protein) (FtsE-FtsX), required for CwlO activity (cell elongation) and for proper activation of Spo0A and initiation of sporulation
Locus
BSU35250
Isoelectric point
10.02
Molecular weight
32.00 kDa
Function
control of cell wall synthesis
Product
ABC transporter (membrane protein)
Essential
no
Synonyms

Genomic Context

      
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Categories containing this gene/protein

Categories containing this gene/protein

This gene is a member of the following regulons

Gene

Phenotypes of a mutant

  • a ftsX mutation is synthetically lethal with a lytE mutation (due to a lack of autolysin activity) PubMed
  • shorter, fatter cells, this can be rescued by addition of Mg(2+) PubMed
  • reduced growth rate, especially at low Mg(2+) concentrations PubMed
  • The protein

    Catalyzed reaction/ biological activity

  • necessary for the autolysin activity of CwlO PubMed
  • Protein family

  • FtsX subfamily (according to Swiss-Prot)
  • Localization

  • cell membrane PubMed
  • Interactions

    Expression and Regulation

    Operon

  • ftsE-ftsX (according to DBTBS)
  • Regulation

  • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism

  • Spo0A: transcription repression PubMed
  • References

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