SubtiBank SubtiBank
lytB
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lytB

modifier protein of major autolysin LytC
Locus
BSU_35630
Isoelectric point
9.84
Molecular weight
76.55 kDa
Protein length
705 aa Sequence Blast
Gene length
2118 bp Sequence Blast
Function
autolysis
Product
modifier protein of major autolysin LytC
Essential
no
Synonyms
cwbA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Cell envelope and cell division → Cell wall degradation/ turnover → Autolysis
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    3,660,648 → 3,662,765

    The protein

    Structure

  • 4RWR (B. anthracis SpoIID, corresponds to aa 414 ... 702) PubMed

    • Localization

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    Genes
    lytA-lytB-lytC
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • SigD: sigma factor, PubMed, in SigD regulon

    • Regulatory mechanism

  • SinR: repression, in SinR regulon
  • YvrHb: repression, PubMed, in YvrHb regulon
  • SlrR: repression, (in complex with SinR) PubMed, in SlrR regulon
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    Biological materials

    Mutant

  • 1A789 ( lytB::kan), PubMed, available at BGSC
  • BKE35630 (ΔlytB::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAAATTTCAGGTTCCTCCC, downstream forward: _UP4_TGATTATTTTAGGATATAAC
  • BKK35630 (ΔlytB::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CAAAATTTCAGGTTCCTCCC, downstream forward: _UP4_TGATTATTTTAGGATATAAC

    • References

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