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sodF [2019-08-05 09:11:09]
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sodF [2019-08-05 09:11:09]

superoxide dismutase
locus
BSU_19330
pI
6.17
mw
33.32 kDa
protein length
281 aa Sequence Blast
gene length
846 bp Sequence Blast
function
detoxification of oxygen radicals
product
superoxide dismutase
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

    • Gene

    Coordinates
    2,104,056 → 2,104,901

    The protein

    Catalyzed reaction/ biological activity

  • 2 superoxide + 2 H+ = O2 + H2O2 (according to Swiss-Prot)

    • Protein family

  • iron/manganese superoxide dismutase family (with [protein|6153A07B961017052E1072944B59F510D80CEC0F|SodA], according to UniProt)

    • Paralogous protein(s)

  • [protein|6153A07B961017052E1072944B59F510D80CEC0F|SodA]

    • [SW|Cofactors]

  • contains an iron-sulfur cluster

    • Structure

  • [PDB|3EVK] (aa 80 ... 280, from Pyrobaculum aerophilum, 54% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|24EB23F594F2B0EEA2E055857BA14FD9E361E0FD|sqhC]-[gene|E0645DD4A7A871457300139A7E5986EF11C07387|sodF]
    description
    [Pubmed|18436644]

    sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15699190,18436644], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]

    • regulation

  • expressed during sporulation in the mother cell [Pubmed|18436644]
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    Biological materials

    Mutant

  • BKE19330 (Δ[gene|E0645DD4A7A871457300139A7E5986EF11C07387|sodF]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE19330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATTGAACATCTCCGCTTGAT, downstream forward: _UP4_TAAAAAAAGCCCCCTTTCCT
  • BKK19330 (Δ[gene|E0645DD4A7A871457300139A7E5986EF11C07387|sodF]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK19330 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATTGAACATCTCCGCTTGAT, downstream forward: _UP4_TAAAAAAAGCCCCCTTTCCT

    • References

  • 18436644