araB [Mon Aug 31 2015 13:56:09 GMT+0200 (CEST)]

L-ribulokinase

locus: BSU28790

pI: 5.23

mw: 60.00 kDa

function: arabinose utilization

product: L-ribulokinase

essential: no

ec: 2.7.1.16

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.6|Utilization of arabinan/ arabinose/ arabitol]

[SW|Categories] containing this gene/protein

• [SW|utilization of specific carbon sources]

This gene is a member of the following [SW|regulons]

• [SW|AraR regulon], [SW|CcpA regulon]

The protein

Catalyzed reaction/ biological activity

• ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate (according to Swiss-Prot)

Protein family

• ribulokinase family (according to Swiss-Prot)

Structure

• [PDB|3QDK] (''B. halodurans'' AraB)

Expression and Regulation

Operon

• ''[protein|search|araA]-[protein|search|araB]-[protein|search|araD]-[protein|search|araL]-[protein|search|araM]-[protein|search|araN]-[protein|search|araP]-[protein|search|araQ]-[protein|search|abfA]'' [Pubmed|9084180]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|9084180]

Regulation

• repressed by glucose ([protein|search|CcpA]) [Pubmed|12949161]
• induced by arabinose ([protein|search|AraR]) [Pubmed|10417639]

Regulatory mechanism

• [protein|search|CcpA]: transcription repression [Pubmed|12949161]
• [protein|search|AraR]: transcription repression [Pubmed|10417639]

References

• 2500424,9084180,10417639,12949161,9084180